这项发现为我们提供了一个全新的视角来评估免疫治疗的长期效果。通过检测患者肿瘤组织中前体耗竭性T细胞（Texp）的比例，我们或许能够更准确地预测他们未来复发的风险，从而为制定更个体化的治疗和随访策略提供依据。

肿瘤浸润调节性T细胞（Tumor-infiltrating regulatory T cells，TI-Treg cells）是肿瘤微环境中抑制抗肿瘤免疫并促进肿瘤进展的关键免疫细胞。尽管已有多种疗法旨在靶向TI-Treg细胞，然而大多数治疗效果不佳，且可能伴随诱发免疫相关不良事件的风险。

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...

For the 80 million people worldwide with celiac disease, the only treatment available is to cut grains like pasta and bread out of their lives. | For the 80 million people worldwide who have celiac ...

Ten years of substantial work by Université de Montréal immunologist Nathalie Labrecque's team at the Montreal Clinical ...

Dr. Emily Thornton, co-corresponding author of the study said, "This work focuses on the intestine, but effector T reg cells ...

Shipra Das, an immunooncologist at Cellectis, discussed a novel approach using transcription activation-like effector nucleases (TALENs) gene editing to overcome these shortcomings by making CAR T ...

"I think it may be possible to stop the drug and then restart it or to give it much less often," she said. OX40R is a co-stimulatory molecule expressed on activated effector and memory T cells, and ...

We are interested in further understanding the molecular and cellular mechanisms involved in NK cell development, effector function, and generation of memory. We have recently demonstrated that ...