The findings help elucidate what happens during the earliest periods in development. “I was always interested in how cells decide their fate,” Zernicka-Goetz said. In the mouse developing embryo, she ...

Cell Lineage and Fate Determination , edited by ... Likewise, determination refers to what will happen to an embryonic region during normal development, as depicted on a fate map, but it is ...

The diversity we observe arises due to differentiation—a process during development ... change their fate if necessary. However, once the embryo develops further and these cells ...

View Full Profile. Learn about our Editorial Policies. During embryonic stem cell (ESC) development, pluripotent stem cells transition from a naïve state into a primed state before they take their ...

This dynamic period of early development sees embryonic cells displaying remarkable ... “This approach offers a novel way to influence cell fate, such as directing stem cell differentiation ...

As an embryo grows ... Barriga and colleagues found that cells of the neural crest are directed by internal electric fields during development, much like drivers follow the signals of a traffic ...

This dynamic period of early development sees embryonic cells displaying remarkable plasticity ... “This approach offers a novel way to influence cell fate, such as directing stem cell differentiation ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

Protein modifications are key to cell survival because they ensure ... between less OGT activity and more severe effects on embryonic development. Their results showed that OGT played an important ...