As well as providing energy to the cell, glycolysis also controls cell fate in early embryonic development, laying the ...

Glycolysis is an ancient metabolic activity. It consists of a set of reactions that convert glucose into energy. This central ...

The findings help elucidate what happens during the earliest periods in development. “I was always interested in how cells decide their fate,” Zernicka-Goetz said. In the mouse developing embryo, she ...

My research leverages stem cells and induced cell fate change to study early development with a focus on epigenetics and post-transcriptional regulation. During both development and homeostasis, ...

Now, studies suggest that their presence or absence — which can be influenced by external factors, such as environment and diet — can determine the fate of a cell and, in turn, the development of an ...

As division continues, some cells divide into the growing mass, distinguishing cells that form the embryo (epiblast) from those that form the placenta (trophectoderm). Further cell divisions lead to ...

"This approach offers a novel way to influence cell fate, such as directing stem ... this study has generated an unprecedented dataset. Early embryo development is a highly dynamic process that ...

They could tell apart the mRNA that was made from the embryo itself and the ... molecular mechanisms underlying cell fate determination during embryonic development.” They hope that their ...

The first few days of a human embryo ... known as single-cell RNA sequencing to produce a complete atlas of the genes involved in the guinea pig pre-implantation development, and examined ...