Can a single protein-encoding gene determine whether a vertebrate embryo develops normally ... that suppression of Pcdh8 is essential for the notochord to elongate properly in zebrafish.
For the first time, scientists at the Francis Crick Institute have successfully developed human stem cell models that include a functional notochord—a crucial tissue in embryonic development ...
Many four-legged animals go through embryonic stages that have similar features -- gill arches, a notochord, segmentation, and paddle-like limb buds -- as they develop into different adults.
In most creatures with backbones, vertebrae replace the notochord in the embryonic stage of development. But the coelacanth has no fully formed vertebrae, and so the notochord provides its ...
This paper describes how the vertebrate version of the hedgehog gene-as expressed by the notochord (an embryonic structure)-induces the formation of floor plate cells and motor neurons in the ...
Due to its proximity to the dorsal endoderm, the notochord has been the prime candidate for directing pancreatic development. Although initial in vitro experiments confirmed this prediction ...
Zebrafish embryos with a normally formed notochord and an abnormal, severely shortened notochord. News organizations may use or redistribute this image, with proper attribution, as part of news ...
When Schwann heard about the nucleus, he realized that he had seen a similar structure in the vertebrate notochord—a rodlike structure in the embryo that develops into the spinal column. Sure enough, ...