Knowledge of a drug's mechanism of action enables better dosing through monitoring of the drug's effects on the target pathway in the patient. For example, the proper statin dosage for a given ...

Esketamine, a nasal spray formulation of the S-enantiomer of ketamine, offers a novel mechanism of action, providing rapid relief for patients who have not responded to traditional antidepressants.

Enzyme mechanisms are the chemical transformations, and the steps within them, generated by enzymatic action on substrates. The mechanism of enzyme catalysis is similar in principle to other types ...

Buoyed by data from VENTURA showing that aticaprant was safe and well-tolerated, and the potential for its mechanism of action ... and MDD therapy Spravato (esketamine), which made more than ...