Newly discovered estrogen receptor-dependent signaling pathways demonstrate that estrogen functions in the cytosol as well as in the nucleus. The classic estrogen receptor signaling pathway occurs ...

The confirmed and promising osteoporosis susceptibility genes are clustered in three biological pathways: the estrogen endocrine pathway, the Wnt/β-catenin signaling pathway, and the RANK/RANKL ...

A new study led by scientists at Weill Cornell Medicine has revealed that the hormone estrogen plays a key role in binge ...

Estrogen functions through binding of two different ... Inhibiting bone resorption via an effect on the RANK/RANKL/OPG signaling pathway (see following section); Enhancing bone formation by ...

Regarding targeting estrogenic pathways, evidence indicates that kaempferol antagonizes estrogen-mediated breast cancer cell proliferation by upregulating the expression of cathepsin, cyclin D1 ...