Newly discovered estrogen receptor-dependent signaling pathways demonstrate that estrogen functions in the cytosol as well as in the nucleus. The classic estrogen receptor signaling pathway occurs ...

A multistep pathway, involving phosphorylation of pRB ... Although it opposes estrogen activity in the breast, it is an estrogen mimetic in the uterus, an important consideration in its ...

Estrogen functions through binding of two different ... Inhibiting bone resorption via an effect on the RANK/RANKL/OPG signaling pathway (see following section); Enhancing bone formation by ...

A new study led by scientists at Weill Cornell Medicine has revealed that the hormone estrogen plays a key role in binge ...

The confirmed and promising osteoporosis susceptibility genes are clustered in three biological pathways: the estrogen endocrine pathway, the Wnt/β-catenin signaling pathway, and the RANK/RANKL ...

Regarding targeting estrogenic pathways, evidence indicates that kaempferol antagonizes estrogen-mediated breast cancer cell proliferation by upregulating the expression of cathepsin, cyclin D1 ...