Large Subunit rRNAs: The large subunit in prokaryotes contains the 23S and 5S rRNAs, while in eukaryotes, it contains the 28S ... The rRNA structures also provide binding sites for ribosomal proteins, ...

Since eukaryotic ribosomes have a different structure, these antibiotics do not significantly affect them, making them effective against bacterial infections. Prokaryotic protein synthesis offers ...

Zhang. More information: Jing Cheng et al, Capturing eukaryotic ribosome dynamics in situ at high resolution, Nature Structural & Molecular Biology (2025). DOI: 10.1038/s41594-024-01454-9 Provided ...