and Furuichi et al., revealed that certain viral and eukaryotic mRNAs have a cap — a methylated guanosine residue linked to the 5′ end of mRNA through an inverted 5′ to 5′ triphosphate bridge.

The hydrolysis of the cap to a 5′-monophosphate is the first committed step in eukaryotic mRNA decay, and now a study by Celesnik et al. 1 in Molecular Cell shows that a remarkably similar ...

As a single-subunit enzyme, FCE contains all the enzymatic activities to achieve a Cap-0 structure, a critical step in eukaryotic mRNA maturation. When used in conjunction with NEB's mRNA Cap ...

You can expect three times the transcriptional yield (4 mg/mL) and a much-improved capping efficiency (>95%) over traditional methods. The mRNA cap structure is an important point of consideration for ...

Abe's team overcame this hurdle by introducing a cap structure into the circular mRNA itself. This internal cap structure ...

Protein synthesis refers to the process by which cells construct proteins. It's a fundamental cellular mechanism for all living organisms, as proteins carry out enzymatic activities, structural ...