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Study reveals FUS protein's role in two neurodegenerative diseases
Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two devastating neurodegenerative diseases. Scientists have long suspected a protein called FUS might play a role ...
AZoLifeSciences on MSN6mon
The Complex Link Between DNA Modification and ALS
the researchers found that inhibiting PARylation or reducing H1.2 levels alleviates ALS-related changes such as the ...
The Scientist1y
An Ancient Viral Protein May Play a Key Role in ALS
1 Some ALS patients also experience cognitive decline and behavioral changes. Gag-pol contains a retroviral protease domain, which it uses to cut itself and the gag form into pieces. Using a ...
Nature5y
Administration of heat shock protein 70 delays disease progression in model of ALS
A number of studies have shown that motor neurons are unable to mount a complete stress response as they lack the capacity to upregulate heat shock protein 70 (HSP70). Furthermore, HSP70 has been ...