In atherosclerosis ... followed by a chronic process that provides an essential fibrous cap that prevents plaque rupture. With the recognition of the essential involvement of VSMC proliferation ...

with a correspondingly thin fibrous cap — a vulnerable plaque prone to rupture and thrombosis. Atherosclerotic plaques typically progress to the advancing atheroma stage at age 55 years to 65 years.

The research team found that atherosclerotic plaques from patients with type ... Dysregulation of MMP2-dependent TGF-ß2 activation impairs fibrous cap formation in type 2 diabetes-associated ...

Some atherosclerotic plaques have a stable fibrous cap; others, with a thin cap, are considered “vulnerable.” Unfortunately, only a few research centers have access to the techniques and ...

They also observed larger necrotic cores, thinner fibrous caps, and greater immune cell content. These findings indicate the development of vulnerable atherosclerotic plaques that are at higher ...

Atherosclerosis is the build-up of fatty material (such as cholesterol), fibrous material and calcium). The build-up forms an atheroma (degeneration of the walls of the arteries) under the ...

Features of Advanced Atherosclerotic Plaques Thin-cap fibroatheroma composed of a large lipid core, thin fibrous cap and shoulder regions with a high density of inflammatory cells and microvessels ...