The first CF rat model, CFTR tm1sage (termed CFTR-/- or KO), was designed in collaboration with SAGE (now Horizon Discovery) and subsequently characterized at UAB and distributed to the CF community.

Five groups are now working together to assemble, annotate and release an updated version of the rat genome. As the prevailing model for physiology, complex disease and pharmacological studies ...

Marrow implants harvested 3 weeks after implantation showed small foci of woven bone. However, the tissue was confined to the periphery of the implant, with the interior remaining acellular (Fig 2 ...