Nature2 个月
G-protein-coupled inwardly rectifying potassium channels are targets of alcohol action
β subunits of GABA A receptors form proton-gated chloride channels: Insights into the molecular basis Figure 1: Ethanol potentiates a potassium current induced by rapid activation of GABA B ...
Royal Society of Chemistry4 年
Nobel Prize for Chemistry awarded for G-protein-coupled receptors
The 2012 Nobel Prize for Chemistry has been awarded to Robert Lefkowitz and Brian Kobilka for groundbreaking discoveries that reveal the inner workings of G-protein-coupled receptors. Professor David ...
来自MSN1 个月
Scientists Design Ultra-Stable Synthetic Proteins That Could Change Drug Discovery
focusing on G protein-coupled receptors (GPCRs), which are vital for cell signaling and drug discovery. The researchers employed computational tools to re-engineer the adenosine A2A receptor and ...