In downstream processing of biopharmaceutical products, protein aggregation presents one of the main risks in terms of ...

To overcome these limitations, scientists developed the real-time quaking-induced conversion (RT-QuIC) assay for both research and diagnostic use, where prion seeds taken from specimens induce protein ...

These molecules are key players in health and disease. One such molecular switch is G protein-coupled receptor kinases, or GRKs for short. Their involvement in a broad range of diseases makes GRKs ...

D dysfunction in protein clearance systems (e.g., autophagy) may further contribute to aggregation. 3 In addition, chronic ...

This newly published analysis in Genes & Diseases sheds light on the crucial role of mechanosensitive adhesion G ...