Membrane receptors fall into three major classes: G-protein-coupled receptors ... signals and molecules within the cell, they permit signaling molecules to affect cell function without actually ...

G-protein coupled receptors regulate hormone ... role of GPCRs in islet biology and hormone secretion, and how signaling in the cell through these receptors is disrupted in diabetes.

G Protein-Coupled Receptors (GPCRs) in advancing GPCR-targeted therapies, including the use of agonists, antagonists, biased ...

Proteins interacting with cell membranes play a vital role in countless biological processes, from how cells communicate to ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

This newly published analysis in Genes & Diseases sheds light on the crucial role of mechanosensitive adhesion G ...

Host cells activate cell death pathways in response to bacterial manipulation of innate immune signalling, but the molecular ...

They are the building blocks of life, performing a wide range of functions within organisms, from catalyzing metabolic reactions to providing structural support and enabling cell signaling. Proteins ...

A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts.