By removing a gene to stunt cane toads at their tadpole stage, scientists hope they may have found a way to make the invader ...

Permanent change in DNA leading to the loss of function of a gene, caused by a manipulation of the organism's DNA in a laboratory followed by breeding to produce a population of organisms that are ...

Although both approaches ultimately interfere with gene function, knockout and knockdown techniques accomplish this through distinct mechanisms that operate at different levels. Gene Knockdown: A ...

Both gene knockout and knock-in models are powerful tools widely used in biomedical research to gain important insights into ...

The Ca2+ stored in the cellular endoplasmic reticulum (ER) plays a crucial role in protein folding and lipid transfer, and its impairment leads to cellular ER stress. When chronic cellular ER stress ...

Synthego, a leading genome engineering solutions company, today announced the launch of the Gene Knockout Kit v2. This is the only product that leverages a novel ...

The Knockout Mouse Phenotyping Program (KOMP2) sites at Baylor College of Medicine, Jackson Laboratory, and University of California, Davis, are collaborating with the International Mouse Phenotyping ...

Research led by Children's Hospital of Fudan University in China has found that a gene called pancreatic progenitor cell ...

This study achieved CRISPR/Cas9-mediated genome editing in grass carp (Ctenopharyngodon idella), China's most economically vital freshwater fish.