When miRNA acts as the guide for RNAi, only a short part of the molecule ... This often results in a 100 percent match between guide and target, with very low off-target activity. Additionally, siRNAs ...

Various gene silencing technologies like siRNA, miRNA, ribozymes, DNAzymes have shown promise as therapeutics agents against viral diseases. RNAi-based drugs against viruses such as ebola virus ...

RNAi is widely used to study gene function by selectively silencing specific genes and observing the resulting phenotypes ... and genetic disorders. By designing siRNAs or miRNA mimics that target ...