To preserve genome integrity and proper cell-cycle progression, eukaryotic cells have developed checkpoint functions that are constantly monitoring DNA integrity and that serve to coordinate ...

Genome and mutations DNA replication is carefully controlled to preserve the genetic information. However, changes in the genome do sometimes occur. These changes are known as mutations.

Stay tuned! See Personal Genome Project. THIS DEFINITION IS FOR PERSONAL USE ONLY. All other reproduction requires permission.

Depending on the definition, a gene may be considered a stretch of DNA that acts as instructions for protein production. Regions of DNA that do not code for proteins may also be considered genes if ...

See Human Genome Project. THIS DEFINITION IS FOR PERSONAL USE ONLY. All other reproduction requires permission.

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

This is by far the most common use of CRISPR. It’s called genome editing – or gene editing – but usually the results are not as precise as that term implies. CRISPR can also be used to make ...