coli, with far-reaching implications for how all cells maintain genomic stability. The findings demonstrate that, under certain circumstances, the RNA polymerase (RNAP) enzyme responsible for ...

Centre for Genome Stability (CGS) is a unique multidisciplinary programme bringing together experts from across the ICR and The Royal Marsden who work on DNA-damage response and genome instability ...

“It appears that RapA and Rho work as complementary—not redundant—safeguards for genome stability when E. coli are subject to high-salt stress.” The implications could be vast ...

The red sea urchin (Mesocentrotus franciscanus) is one of the earth's longest-living animals, reported to live more than 100 years without showing signs of aging. To further understand the genetic ...

Such regulation is critical for cell survival and genetic fidelity. We further determined the regulatory pathway and the molecular mechanisms by which the ATM/ATR homolog regulates dNTP levels and ...