Glial cells come in many forms, but three major types are currently recognized: astrocytes, oligodendrocytes and microglia. The first are primarily involved in creating the blood-brain barrier and ...
"We knew essentially nothing about the interactions between glial cells and dendrites, but they matter just as much as axons," Shaham says. "You need something to receive signals, too." The team ...
Deletion of the ‘glial cells missing-2’ gene in mice disrupts development of the parathyroid glands but does not eliminate production of parathyroid hormone (PTH), which is required for ...
Traumatic brain injury, stroke, and degenerative diseases elicit complex pathogenic cascades involving glial cells such as astrocytes, microglia, and ...
Pharmaceutical companies ramp up efforts to get the brain’s immune cells to help treat Alzheimer’s disease and other conditions, but not everyone agrees the approach will be effective.
Neurons may get all the glory, but they would be nothing without glial cells. While brain cells do the heavy lifting in the nervous system, it's the glia that provide nutrients, clean up waste ...
In both cases, we made fundamental observations about the nature of glial cells and directly applied these paradigms to relevant neurological diseases: brain tumors and white matter injury. Our view ...
Despite substantial efforts, the molecular mechanisms by which 25-OHC affects glial cells in diseases like amyotrophic lateral sclerosis (ALS) remain unclear. Against this backdrop, a research ...
In a recently published review, researchers led by Prof. Wu Qingfeng at the Institute of Genetics and Developmental Biology ...
Michael Barresi’s research interests are focused on how glial cells help wire the nervous system in the embryonic zebrafish brain. His lab discovered that astroglial cells provide a substrate for ...
Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...