The HBV genome is an extremely compact structure (~3 kb), which encompasses four overlapping ORFs encoding for viral polymerase/reverse transcriptase; the capsid-forming core protein; three ...
Median HBV DNA at baseline in these eight ... which led to a frameshift. Core promoter, precore and core regions. The core protein was found to be mutated in five of the eight patients in their ...
Moreover, each step in the flow of information from DNA to RNA to protein provides the cell with a potential control point for self-regulating its functions by adjusting the amount and type of ...
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