Part of the HBV polymerase gene flanking the YMDD motif was sequenced after polymerase chain reaction (PCR) amplification. Meanwhile, 20-24 clones were selected at random from each sample and YMDD ...

but selection of HBV polymerase mutants with enhanced replication by lamivudine treatment has also been reported. [19] In the present study, the mean values of HBV DNA levels of the five patients ...