rcDNA 经宿主滞后链合成机制修复为完全双链的共价闭合环形 DNA（cccDNA），人体细胞中的组蛋白迅速沉积于 cccDNA 形成微型染色体，作为 HBV 病毒转录 ...

Precision BioSciences has reported initial outcomes from the ELIMINATE-B trial of PBGENE-HBV, a gene editing programme for treating chronic Hepatitis B patients who are HBeAg-negative. In cohort ...