Chromosomal instability plays a crucial role in the progression of cancer ... the transcriptome and cell surface proteins. The researchers uncovered an enormous cellular and molecular ...

This heterogeneity is a major obstacle ... is tackling by examining the transcriptome and epigenome of single cancer cells pre- and post-treatment. “Single-cell RNA-sequencing allows us to ...

The following is a summary of "Prediction of radiosensitivity in non-small cell lung cancer based on computed tomography and tumor genomics: a multiple real-world cohort study," published in the April ...

This tumour heterogeneity is one of the biggest challenges for ... We have developed techniques that can recognise and measure cancer-associated transcriptome instability, enabling better ...

The analyses of biomarkers in body fluids offers a minimally invasive and easily repeatable way to detect cancer-associated changes in the genome, epigenome, transcriptome and proteome.

well-characterized cancer-specific markers can be used to screen the entire prostate tissue to assess molecular differences in individual tumor foci. A clearer understanding of foci-specific molecular ...

providing unprecedented insights into cellular heterogeneity and function. Unlike traditional sequencing methods that analyze bulk samples containing millions of cells, single-cell sequencing enables ...