This fourth known histamine receptor now provides an attractive drug ... the H2 and H3 receptors act mainly in the digestive system and brain, respectively. Even with the knowledge of these ...

Vogt produce histamine synthetically by removing the ... 1972—James Black discovers the H2 receptor and characterizes its antagonist, burimamide. 1999—Researchers at a subsidiary of Johnson ...

H3 histamine receptors are involved in the central nervous system and are believed to help regulate dopamine and other neurotransmitters. H4 receptors are involved in the formation of blood cells.