This fourth known histamine receptor now provides an attractive drug ... the H2 and H3 receptors act mainly in the digestive system and brain, respectively. Even with the knowledge of these ...

H3 histamine receptors are involved in the central nervous system and are believed to help regulate dopamine and other neurotransmitters. H4 receptors are involved in the formation of blood cells.

IL-17A signals through its receptor, IL-17RA, which is expressed in many peripheral tissues; however, expression of IL-17RA in the central nervous system (CNS) and its role in CNS inflammation are ...