LBH589 is a novel pan-histone deacetylase (HDAC) inhibitor that has potent antitumor activity in multiple myeloma and other hematological malignancies. However, its impact on the immune system has ...

This Review focuses on the family of histone deacetylases (HDACs ... Suramin has been shown to be a weak inhibitor of SIRT5 deacetylase as well. No SIRT3-selective inhibitors have yet been ...