Histone deacetylases (HDACs ... Suramin has been shown to be a weak inhibitor of SIRT5 deacetylase as well. No SIRT3-selective inhibitors have yet been identified. The therapeutic application ...

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Eight months after announcing the $18.5 million first tranche of its series A, Augustine Therapeutics has closed the oversubscribed round at $85 million and is now ready to begin clinical development ...

Immunoprecipitation of histone deacetylase activity from cell extracts. We carried out immunoprecipitations as described above with Hela nuclear extracts (50μl; Computer Cell Culture Centre ...