Immunoprecipitation of histone deacetylase activity from cell extracts. We carried out immunoprecipitations as described above with Hela nuclear extracts (50μl; Computer Cell Culture Centre ...

Discover how histone modifications unlock secrets of human aging, rivaling the precision of DNA methylation in decoding biological age. In a recent study published in the journal Science Advances ...

The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed ...