Comparative analyses of mouse and human genomes have provided insight into our common features and have guided powerful genomic manipulations in the mouse to generate models of human pathologies.

Although mouse IL-7 and IL-15 are both considered to be cross-reactive with their cognate human receptors, several groups have shown that lymphopoiesis in HIS mice is limited by the availability ...

They fertilized the eggs with ordinary mouse sperm and implanted them in surrogate mouse moms. The experiment was repeated ...

Furthering their analysis, the researchers tested the impact of PD-1 humanization in mice—replacing mouse PD-1 with the human ...

The Knockout Mouse Phenotyping Program (KOMP2) sites at Baylor College of Medicine, Jackson Laboratory, and University of California, Davis, are collaborating with the International Mouse Phenotyping ...

However, he stresses that the team's findings are currently based on mouse models, meaning human trials are still a long way off, and potential treatments even further down the line. "It is a long ...

Researchers at the Advanced Research Unit on Metabolism, Development & Aging (ARUMDA), in the Tata Institute of Fundamental Research (TIFR, Mumbai and ...