The spectacular success of the Human Genome Project suggests that a systematic effort in high-throughput structural genomics may be able to do it better, faster and cheaper. Unfortunately ...

Through genome sequencing ... potentially improving the classification of structural variants in human genomes as either benign or clinically significant. Both studies reached similar conclusions ...

Am J Hum Genet 79, 439-48 (2006) Lupski, J. R. Genomic disorders: Structural features of the genome can lead to DNA rearrangements and human disease traits. Trends in Genetics 14, 417-422 (1998 ...

The genetic information in an organism is called its genome. The Human Genome Project, or HGP for short, was started at the end of the last century. It was very ambitious and had several aims ...

Jude Children's Research Hospital used cryo-electron microscopy (cryo-EM) to obtain fine structural details of a human chromatin ... to understand how our genome is expressed." ...