The team hoped that sulfatase would catalyse the required hydrolysis reaction, involving the addition ... of a chain of small molecules called amino acids. Once the protein chain is formed ...

Did you ever take a swig of aspartame-sweetened diet soda and have it taste nasty? Sour, metallic, and vile, but not sweet.

Credit: COURTESY OF THE SMITHSONIAN INSTITUTION Frederick Sanger presented the first complete amino acid sequence of a protein (insulin) after 12 years of painstaking biochemistry involving partial ...

Hydrolysis is one of the more efficient chemical reactions that convert long chain ... as well as in proteins for the production of amino acids and peptides,” concludes Tsubaki.

New research uses AI to engineer enzymes with intricate active sites, expanding the possibilities for synthetic biocatalysts.

Hydrolysis is one of the more efficient chemical reactions that convert long chain ... as well as in proteins for the production of amino acids and peptides," concludes Tsubaki.

New research represents a notable step forward in designing enzymes from scratch. With their approach, the authors designed an enzyme that uses a covalent intermediate to catalyze a two-step reaction, ...