But, new evidence strongly supports the use of NIV for patients with advanced COPD and persistent hypercapnia. The study 2, supported by funding and products by Philips Respironics and ResMed ...

Background: The pathogenesis of daytime hypercapnia (PaCO 2 ≥ 45 mm Hg) may be directly linked to the existence of obstructive sleep apnea syndrome (OSAS) per se, although only some patients ...

and patients with previously stable COPD periodically have exacerbations, including increased dyspnea, cough, worsening hypoxemia or hypercapnia, increased volume or purulence of sputum ...