Immunogenicity of Protein Therapeutics: Therapeutic proteins are susceptible to aggregation in response to a wide variety of stresses encountered during their manufacture, storage and delivery to ...

Protein therapeutics add another layer of complexity to the problem. Components in protein therapeutics may form aggregates in response to pharmaceutically-relevant time scales or under stress ...

Understanding these mechanisms opens new avenues for therapeutic strategies aimed at halting or slowing disease progression by targeting the spread of protein aggregates. The research team is ...

mRNA therapies are one of the hottest drug classes today, but scientists need to solve issues of stability, immunogenicity ... protein that it encodes. mRNA can only exert its therapeutic effects ...

“The rapid nature of our vaccine and therapeutic protein production unlocks many ... inducing broader/ stronger immunogenicity than that achieved with a different licensed vaccine and ...