Cerulein or alcohol decreases pancreatic TFEB, resulting in impaired lysosomal biogenesis and insufficient autophagy. Autophagy may selectively remove damaged mitochondria (mitophagy), abnormal ER ...
In 2000, it was suggested to me that “Autophagy will be the wave of the future; it will become the new apoptosis.” Few people would have agreed at the time, but this statement turned out to be ...
Hence, this is one of the most important processes in our body. Impaired autophagy is linked to cardiovascular diseases, ...
Aging involves gradual functional decline across various biological systems, including impaired cellular mechanisms such as ...