Research on how intracellular bacteria take control of their hosts is not only informing scientists about how these microbes cause disease, but revealing secrets of mammalian biology, says Mukherjee, ...

The result? There are high-value intracellular targets that neither modality can hit. Without being able to reach these ‘undruggable’ intracellular targets, many of the best-validated drivers ...

Tetsuya Muramoto The study revealed the mechanisms by which periodic intracellular cAMP signal ... Optogenetic control of cAMP oscillations reveals frequency-selective transcription factor ...

Intracellular checkpoint molecules like BIM ... and its inhibition can improve NK cell-mediated control of tumor metastasis. CIS, a negative regulator of IL-15 signaling, is upregulated by ...

The study revealed the mechanisms by which periodic intracellular cAMP signal frequencies ... More information: Kensuke Yamashita et al, Optogenetic control of cAMP oscillations reveals frequency ...