N-terminal kinase exerts a cross-tissue therapeutic effect on metabolic dysfunction induced by sucrose overconsumption in rats.

【导读】子宫内膜癌（EC）是威胁妇女健康的重大疾病，治疗后的复发是一大挑战。虽然胆固醇代谢异常被认为与子宫内膜癌的进展有关，但其潜在机制仍不清楚。在这项研究中，团队发现羊毛甾醇合成酶（LSS）是与乳腺癌相关的胆固醇代谢的关键介质。2025年2月8日， ...

In addition to ERK, two other MAPK pathways are crucial in immune cells: the JUN N-terminal kinase (JNK; also known as MAPK8) pathway and the p38 (also known as MAPK14) pathway, both of which ...

A research team at Toho University, has revealed that cadmium, a toxic heavy metal, increases the synthesis of hyaluronan in vascular endothelial cells. Their study has also identified that this ...

Looking today at week-over-week shares outstanding changes among the universe of ETFs covered at ETF Channel, one standout is the SPDR Bloomberg High Yield Bond ETF (Symbol: JNK) where we have ...

In particular, the MAP kinase pathway was predicted to be upregulated ... the researchers found ERK1/2 and JNK to be hyperactivated in α-synucleinopathy neurons. To assess whether the aberrant ...