Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype known as triple-negative breast cancer (TNBC). This ...

In a recent study published in Nature Metabolism ... increased lipid peroxidation, and fibrosis in the liver. Overall, the LXRα W441R variant was found to result in hepatotoxicity, characterized ...

Image Caption: Dysregulation of lipid metabolism promotes EMT (by Figdraw). Down-regulation of ELOVL2 promotes EMT in breast cancer by up-regulating expression of SREBP1/2. Genes & Diseases ...

Apolipoproteins have many roles in lipid metabolism, which are presented in Table II. Table III lists several major enzymes involved in lipoprotein metabolism that have been identified.

Her team is a member of the Research Program Unit, Research Program of Clinical and Molecular Metabolism at the University of Helsinki. Her research team has a focus on lipid lipoprotein metabolism in ...

The findings suggest that lipid metabolism may play a central role in maintaining a healthy immune system as we age. The researchers analyzed gene and protein expression, along with lipid profiles ...

Key enzyme in lipid metabolism linked to immune system aging. ScienceDaily . Retrieved April 20, 2025 from www.sciencedaily.com / releases / 2025 / 04 / 250418112813.htm ...