Junctional epidermolysis bullosa ( JEB) is a variant of EB where the cleavage plane is in the lamina lucida of the epidermal basement membrane. The usually lethal form of JEB is called JEB-Herlitz.
Direct immunofluorescence on a sample of perilesional skin will show linear deposits of IgG on the basement membrane ... 2007) in the lamina lucida. Another common antigen is an 180 kD ...