Objective: Newborns are highly susceptible to bacterial sepsis. Mannan-binding lectin (MBL), M-, L- and H-ficolin recognize microorganisms and activate the complement system via MBL-associated ...

Using its protease engineering platform, Catalyst has advanced two engineered coagulation factors ... disorders of the classical and lectin complement pathways, that are all in advanced discovery ...

He completed his PhD in Biochemistry from University of Oxford. During his doctoral research, Umakhanth investigated the protein-protein interactions leading to the lectin pathway of complement ...

Endothelial damage, which activates the lectin pathway of complement, plays a central role in the development of TA-TMA. The condition occurs in both autologous and allogeneic transplants but is ...