Because effects of leptin were attenuated but not abolished by the CRF receptor antagonist, CRF or urocortin may act in conjunction with other mediators, such as melanocortin, which have been ...

leptin-deficient ob/ob mice and intestine-specific leptin receptor isoform B-deficient mice. These data demonstrate that gastric leptin is upregulated in obese individuals. Results from high-fat ...