The new technique can appropriately be called ‘ligand exchange’. The method combines two fields of chemistry, namely, ion exchange and co-ordination chemistry, in order to accomplish a task ...

Ligand binding controls aromatic side-chain dynamics, enabling tunable fluorescence and supramolecular biomaterials. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news ...

(RTTNews) - Biopharmaceutical company Ligand Pharmaceuticals, Inc. (LGND), while reporting a loss in its fourth quarter, compared to prior year's profit, on Thursday confirmed fiscal 2025 forecast.

Bile acids are natural ligands of FXR, which bind to the ligand-binding pocket (LBP) in the ligand-binding domain (LBD) of FXR, inducing conformational changes that recruit co-activators and ...

The key to this is the modification of the original ligand with a reactive "handle" that allows it to react with a nucleobase at the RNA binding site. This was first demonstrated in vitro and in ...