Ferroptosis, driven by excessive lipid peroxides and iron-dependent reactive oxygen species (ROS), differs from other cell death forms in its immunogenicity. It involves the regulation of the ...

The Farese & Walther laboratory investigates cellular lipid and energy metabolism, in particular the mechanisms and physiology of neutral lipid synthesis and storage in lipid droplets. More broadly ...

Innovative insights into the role of ferroptosis, a unique form of programmed ... have demonstrated the ability to regulate iron metabolism, lipid peroxidation, and redox balance, positioning ...