Researchers explore the cellular and molecular adaptations associated with human secondary lymphoid tissue in adults during ...

胰腺癌（Pancreatic Ductal Adenocarcinoma, PDAC）因其高度侵袭性和极低的生存率，被认为是最具挑战性的癌症之一。尽管近年来免疫治疗技术迅速发展，许多肿瘤仍然被归类为“免疫冷”的状态，意味着肿瘤微环境中缺乏足够的免疫细胞浸润，使得治疗效果受限。然而，研究人员近年来的研究揭示了一个可能突破这一瓶颈的关键——三级淋巴结构（Tertiary Lymphoid Struct ...

Lymphoid proliferations are traditionally thought to be either benign conditions (reactive hyperplasia and lymphadenitis) or malignant lymphomas. However, not all lymphoid lesions at present can ...

Table 2. Distinction between atypical lymphoid proliferations rich in Reed–Sternberg-like cells (reactive immunoblasts) and classic Hodgkin lymphomas. Aspects Atypical lymphoid proliferations ...

A research team at Memorial Sloan Kettering Cancer Center (MSK) has made new insights into how the body forms immune cell clusters called tertiary lymphoid structures (TLSs) in response to foreign ...

A team led by surgeon-scientist Dr. Vinod Balachandran identified the molecular pathway involved in the formation of tertiary lymphoid structures. Therapeutically targeting this pathway could ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

GvL mainly occurs in lymphoid tissues, such as bone marrow and lymph nodes, where the malignant hematological cells reside. GvHD, by contrast, occurs throughout the body after donor T cells become ...