Problems such as poor tumor infiltration, immune suppression, and low immunogenicity have hindered efforts. Cellis has created its macrophage–drug conjugate (MDC) platform to overcome the ...

本综述聚焦于纳米探针技术在肿瘤相关巨噬细胞极化成像中的最新进展，为精准肿瘤学提供了新的视角和工具。 巨噬细胞在人体中无处不在，在免疫监视、炎症反应和组织稳态中发挥着关键作用。其表型可塑性是巨噬细胞的显著特征，使其能够根据局部微环境 ...

1 There are three different macrophage types, naïve (M0), antitumor (M1), and protumor (M2). M1 macrophages accumulate at the tumor and exert antitumor activity. Researchers have attempted to use them ...

Researchers from Moffitt Cancer Center have found a new way to boost cancer immunotherapy by targeting a protein called ...

Researchers from Moffitt Cancer Center have found a new way to boost cancer immunotherapy by targeting a protein called ...

The method triggers immune responses that inhibit melanoma, triple-negative breast cancer, lung carcinoma, and ovarian cancer ...

Researchers have found a new way to boost cancer immunotherapy by targeting a protein called macrophage receptor with collagenous structure, or MARCO. Their study shows that blocking MARCO in ...

Zarif and his colleagues previously demonstrated that macrophage precursor cells called ... glutamine-blocking form inside the tumor, preventing it from causing harmful side effects elsewhere ...

This process formed a feedback loop which resulted in more macrophages being recruited to the tumor, according to the study. The scientists then aimed to inhibit the glioblastoma-macrophage ...

Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related deaths worldwide.

The team's findings were published in the paper "Functional reprogramming of neutrophils within the brain tumor microenvironment by hypoxia-driven histone lactylation," from Cancer Discovery.