In addition, one of the key issues that characterize the current state of antibiotic drug ... antifungal agents are often classified into three groups, depending on their site of action: the ...
Described here are small molecule efforts in the antibacterial and antifungal areas ... in the concentration of the drug target—thus eliminating it as a site of action; changes in molecule ...
With only a few exceptions, these drugs were discovered by screening in animal models which do not discriminate on the basis of mechanism of action. Over the last 35 years, over 34,000 ...
The experience and recommendations of combinational antifungal therapy for cryptococcal ... giving some information on mechanism of action and principles in combined use of mycotic anti-infectives.
3 个月on MSN
Many of the fungi we know are an essential part of nitrogen and carbon recycling in the environment through their action of decomposing ... Another issue is that antifungal drug development ...
The University of Exeter has launched a new round of funding to tackle the growing global challenge of fungal antimicrobial resistance (fAMR). The FAILSAFE project (Fungal AMR Innovations for ...
来自MSN1 个月
Importance of RNA modifications in fungal infection resistance could lead to better treatmentsAn often-overlooked mechanism of gene regulation may be involved in the failure of antifungal drugs in the clinic ... used the known mode of action of fluorocytosine on A. fumigatus as the ...
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