In addition, one of the key issues that characterize the current state of antibiotic drug ... antifungal agents are often classified into three groups, depending on their site of action: the ...

The experience and recommendations of combinational antifungal therapy for cryptococcal ... giving some information on mechanism of action and principles in combined use of mycotic anti-infectives.

An often-overlooked mechanism of gene regulation may be involved in the failure of antifungal drugs in the clinic ... used the known mode of action of fluorocytosine on A. fumigatus as the ...

With only a few exceptions, these drugs were discovered by screening in animal models which do not discriminate on the basis of mechanism of action. Over the last 35 years, over 34,000 ...

Described here are small molecule efforts in the antibacterial and antifungal areas ... in the concentration of the drug target—thus eliminating it as a site of action; changes in molecule ...