Researchers discovered that ALPK2, a heart-specific enzyme, may protect against HFpEF by activating TPM1 in heart muscle ...

Transplantation of bone marrow from mice with heart failure (TAC, meaning transverse aortic constriction) into healthy mice (control) led to cardiac dysfunction, as shown in this echocardiogram.

are powerful markers of adverse outcome, and in particular of the development of heart failure and death. In stable CAD, the risk associated with increased circulating concentrations of BNP and NT ...

When the researchers looked at the hearts of mLOY mice using ultrasound, they noticed the development of cardiomyopathy—a chronic disease of the heart muscle ... and more scar tissue—known as fibrosis ...

A specially designed drug prevented laboratory mice from developing heart failure after heart attacks, according to new research from Cedars-Sinai. This discovery could lead to new treatments to ...

Heart failure with preserved ejection function is ... To understand its role, they compared mice without the gene that creates the enzyme with those that had exceptionally high levels of the ...