Organoids have revolutionized science and medicine, providing platforms for disease modeling, drug testing, and understanding ...

A research group led by Nagoya University Graduate School of Medicine in Japan has uncovered a potential mechanism linking ...

A new study reveals that inflammation during pregnancy may impair neurodevelopment in infants by reducing CD11c-positive ...

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A new organoid model reveals details of the developing nervous system’s response to viral infections, such as Rubella. It ...

More information: Kazuya Fuma et al, Prenatal inflammation impairs early CD11c-positive microglia induction and delays myelination in neurodevelopmental disorders, Communications Biology (2025 ...

Researchers from Charité - Universitätsmedizin Berlin and the Max Delbrück Center have identified the precise mechanism by ...

Knockout of Irg1 in microglia in vivo reduced itaconate levels and exacerbated TBI-associated metabolic changes and inflammation. Microglial Irg1-knockout also worsened some neurological outcomes ...

A research group led by Nagoya University Graduate School of Medicine in Japan has uncovered a potential mechanism linking maternal inflammation to ...

Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...

In the study, Neher and his colleagues studied the response of microglia—long-lived immune cells found only in the brain—to repeated bodily infections. The team injected mice that model Alzheimer’s ...