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Pain processing involves neurons, microglia and astrocytes. The functions of glia extend beyond basic support for neurons. Once activated, they release various classic immune factors that are also ...
In a recent study published in PNAS, Zhang showed that the transcription factor DLX2 can convert astrocytes into progenitors that produce various cell types, including neurons. 3 These findings ...
Their new research in mice, published in iScience02635-X), reveals that cannabinoid receptors located on astrocytes are essential for the brain’s ability to adapt and change early in life ...
Differentiation of iPSCs into neurons, astrocytes, microglia allow us to analyze aberrant gene and protein expression, function and metabolism in developing and maturing human brain before the disease ...
Over the last decade, Dr. Fossati’s lab has developed robust and efficient protocols to generate human oligodendrocytes, astrocytes, microglia, neurons and complex 3D organoid cultures with the full ...